People taking a daily prescribed dose will become dependent on the drug and will have withdrawal symptoms if they stop it. This is not an addiction but instead a physiological response. If you or someone you know is showing these symptoms, it is important to seek professional help immediately. Users and family members should have immediate access to naloxone (Narcan), an opioid agonist medication that rapidly reverses opioid overdose.
- Older people are more likely than younger individuals to experience adverse effects, especially the respiratory depressant effects of fentanyl.
- All information is provided for informational purposes only and is not a substitute for professional medical advice.
- Overdose prevention sites allow individuals to use previously acquired drugs in a safe and supervised space to prevent overdose fatalities (for more on OPS).
- Fentanyl analogs, which are similar in nature to fentanyl and include substances like acetylfentanyl, furanylfentanyl, and carfentanil, have also been found in the US drug supply.
- Naloxone is a lifesaving medication that can reverse an overdose from opioids.
- It’s available both for those who have been prescribed fentanyl and those who are misusing fentanyl.
The Rise And Concern Of Counterfeit Pills

Fentanyl is estimated to be about 100 times more potent than morphine and 50 times more potent than heroin as a pain reliever. It is an effective medication for managing severe pain when properly prescribed and monitored by a clinician. Fentanyl can be illegally mixed into other substances, including heroin, cocaine, ecstasy, and methamphetamine (NIDA, 2021). This combination can result in an individual consuming a much stronger substance than they are used to, resulting in overdose and possibly death.
- If you still have pain after using one lozenge or tablet, your doctor may tell you to use a second lozenge or tablet.
- He went on to recover and was discharged to a rehabilitation program.
- After a fentanyl treatment, you may have side effects that hinder your thinking and reactions or cause dizziness or drowsiness.
- Fentanyl is a strong synthetic opioid that has been used in clinical settings since 1968.
- Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking.
Why Is Fentanyl In The Drug Supply?
Naloxone (Narcan) is an antidote for fentanyl and other opioid overdoses. Naloxone helps reverse the respiratory depression of fentanyl. Naloxone can help prevent fentanyl-related deaths when it is given within a short period of time after an overdose. The nasal spray form of naloxone does not require a prescription and can be obtained from pharmacies. Naloxone acts quickly to reverse the effects of an opioid overdose, but opioids last much longer than naloxone.
Fentanyl, Transdermal Patch
Fortunately, the drug in question here does not kill people. The name of this drug that you can buy in many states without seeing a doctor is known as Naloxone, or Narcan. If there is anyone in your home who uses opioids, it is a good idea to have Narcan on hand. As recommended by this expert, we may soon see Narcan on building walls, next to the fire extinguishers. Fentanyl and other synthetic opioids have now surpassed heroin and prescription painkillers as the deadliest drugs in the United States.
Fentanyl And Overdose
An individual’s tolerance to fentanyl will impact the amount required to cause a fatal overdose. There are two types of fentanyl – pharmaceutical fentanyl and illegally made fentanyl. You can’t overdose by touching an item containing fentanyl. Some medical fentanyl is delivered through skin patches, but it is absorbed slowly over the course of hours. These patches can’t quickly deliver a high dose of fentanyl.

Your pharmacist will provide a prescription by request, or you can have the Mississippi State Department of Health mail a naloxone kit directly to you at no cost. If you or someone you know is at an increased risk for opioid overdose, you should carry naloxone and keep it at home. Several HHS grant programs, such as SAMHSA’s State Opioid Response (SOR) program, allow for the purchase and distribution of naloxone for states and territories. If used correctly, fentanyl test strips can detect the presence of the most common types of fentanyl in street drugs and pills.

Fentanyl Is Potent And Dangerous, But Experts Say Many Myths About Exposure And Risk Do More Harm Than Good
Although fentanyl patches are a legal form of the drug doctors sometimes prescribe for pain, they are easily abused. People may take the gel out of the patch and either put it in their mouth or inject it. When it’s in powdered form, it looks a lot like other powdered drugs such as cocaine. Powdered fentanyl can also be pressed into pills that look like prescription pills such as Percocet or Xanax.

Health Care Providers
“In health care, we dose fentanyl in micrograms,” explains Amanda N. Donald, MD, an addiction medicine physician at Northwestern Medicine. Fentanyl exerts its pain-relieving effects by acting on opioid receptors that occur naturally in the body. Endorphins, the substances in the body that normally bind to opioid receptors and naturally relieve pain, are also connected with “pleasure centers” in the brain. Repeated activation of these centers by narcotic drugs is suspected of playing a role in drug addiction. Hence, fentanyl, similar to other narcotic drugs, carries a high risk of addiction and accidental overdose.
Although most often used to cut powdered opiates, fentanyl is also used to cut pills and drugs like cocaine, ketamine, methamphetamines (like ADHD pills), and benzodiazepines (like Xanax). Before taking fentanyl, be sure to tell your doctor and pharmacist about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use.
Equip workplaces, facilities, job sites, hospitality venues and more with NARCAN® Nasal Spray in case of accidental opioid emergency. To explore additional treatment options, you can view editorially selected providers on our site or visit the SAMHSA Treatment Locator. If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please contact at Browse our directory or reach out to the Substance Abuse and Mental Health Services Administration (SAMHSA) for more information about addiction recovery.
Fentanyl Misuse Is Not Only Dangerous, But Deadly
Learn more about law enforcement and overdose response here. For more information on the core strategies and evidence based interventions, read The Primer on Spending Funds. The DEA and other federal agencies have made a formal commitment to reducing the flow of fentanyl into the US. Trump officials might be experimenting with creating something like a national, MAGA-loyal police force. But as Lopez has detailed time and again, cracking down on supply — as the Portman bill would — doesn’t do anything to address demand or treatment, which many experts name as the bigger issues. Even through the narrow lens of cutting the drug supply, the sellers have already proven adept at adapting to new circumstances.
What Are The Signs Of A Fentanyl Overdose?
It is also important to note that OTC opioids are often misused in combination with other substances, most commonly alcohol, marijuana, and other OTC medications. Complications are more likely to arise when these substances interact with each other. While it would take a much larger amount to overdose on an OTC opioid than on a prescription opioid, it is possible. These medications are never meant to be taken in high doses or long-term.
Over the past decade, fentanyl that is made and distributed illegally has become increasingly common in the illegal drug supply and has contributed to a surge in drug overdose deaths. Typically, a fentanyl overdose manifests as an extrapolation of its pharmacological side effects. Although the clinical scenarios may vary among patients, one of the main concerns is the level of expression of OIRD. In such cases, oxygen administration and respiratory assistance are a priority. An opioid drug antagonist such as naloxone can help to correct OIRD symptoms. Thus, the therapeutic approach should continue until a normal respiratory rate coincides with appropriate oxygen saturation levels.